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Laboratory photo of a mouse retina after receiving OSK gene therapy. Image courtesy of Yuancheng Lu.

Scientists Reverse Age-related Vision Loss and Glaucoma Damage in Mice

December 2, 2020 – Harvard Medical School scientists have successfully restored vision in mice by turning back the clock on aged eye cells in the retina to recapture youthful gene function. The team’s work, described December 2nd in Nature, represents the first demonstration that it may be possible to safely reprogram complex tissues, such as the nerve cells of the eye, to an earlier age. In addition to resetting the cells’ aging clock, the researchers successfully …

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The Genetics of Glaucoma

There has been a remarkable expansion in understanding of the genetic underpinnings of the major forms of glaucoma. As research progresses, we hope to learn much more.